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Editorial Commentary: From Oslo to MARS and the MOON!: Large Anterior Cruciate Ligament Registries Allow Analyses of Revisions and Re-revisions.

Large registry studies are powerful because of inclusion of large numbers of patients. Knee anterior cruciate ligament repeat revision surgery is rare (<10% at 8 years). The reasons require additional investigation. Patients may be counseled that, based on demographic factors, it is difficult to predict who will need re-revision. New publication in Arthroscopy.Read more here.

https://www.lupop.lu.se/article/editorial-commentary-oslo-mars-and-moon-large-anterior-cruciate-ligament-registries-allow-analyses - 2025-10-28

Study-based registers reduce waste in systematic reviewing: discussion and case report

Maintained study-based registers (SBRs) have, at their core, study records linked to, potentially, multiple other records such as references, data sets, standard texts and full-text reports. Such registers can minimise and refine searching, de-duplicating, screening and acquisition of full texts. SBRs can facilitate new review titles/updates and, within seconds, inform the team about the potential

https://www.lupop.lu.se/article/study-based-registers-reduce-waste-systematic-reviewing-discussion-and-case-report - 2025-10-28

Facilitators for using data from a quality registry in local quality improvement work: a cross-sectional survey of the Danish Cardiac Rehabilitation Database.

o investigate use of data from a clinical quality registry for cardiac rehabilitation in Denmark, considering the extent to which data are used for local quality improvement and what facilitates the use of these data, with a particular focus on whether there are differences between frontline staff and managers. New publication in BMJ Open.Read more here.

https://www.lupop.lu.se/article/facilitators-using-data-quality-registry-local-quality-improvement-work-cross-sectional-survey - 2025-10-28

Impact of hip arthroplasty registers on orthopaedic practice and perspectives for the future

Total hip arthroplasty (THA) registers are established in several countries to collect data aiming to improve the results after THA. Monitoring of adverse outcomes after THA has focused mainly on revision surgery, but patient-reported outcomes have also been investigated. New publication in Bone & Joint.Read more here.

https://www.lupop.lu.se/article/impact-hip-arthroplasty-registers-orthopaedic-practice-and-perspectives-future - 2025-10-28

Design and preliminary results of FRENSHOCK 2016: A prospective nationwide multicentre registry on cardiogenic shock

Most data on the epidemiology of cardiogenic shock (CS) have come from patients with acute myocardial infarction admitted to intensive cardiac care units (ICCUs). However, CS can have other aetiologies, and could be managed in intensive care units (ICUs), especially the most severe forms of CS. New publication in Archives of Cardiovascular Diseases.Read more here.

https://www.lupop.lu.se/article/design-and-preliminary-results-frenshock-2016-prospective-nationwide-multicentre-registry - 2025-10-28

National poisoning registers and toxicovigilance in different countries as models for Germany

As of 2019, Germany has still not been able to provide a national poisoning register and toxicovigilance for sufficient and reliable information on human exposure for the purpose of identification and assessment of toxic risk to the public. In particular, the USA acts as a special model, but France, the Netherlands, Switzerland, and Sweden also have efficient poisoning registers and toxicovigilanc

https://www.lupop.lu.se/article/national-poisoning-registers-and-toxicovigilance-different-countries-models-germany - 2025-10-28

Prediction of Lymph Node Metastasis in Breast Cancer by Gene Expression and Clinicopathological Models: Development and Validation within a Population-Based Cohort

More than 70% of patients with breast cancer present with node-negative disease, yet all undergo surgical axillary staging. We aimed to define predictors of nodal metastasis using clinicopathological characteristics (CLINICAL), gene expression data (GEX), and mixed features (MIXED) and to identify patients at low risk of metastasis who might be spared sentinel lymph node biopsy (SLNB). New publica

https://www.lupop.lu.se/article/prediction-lymph-node-metastasis-breast-cancer-gene-expression-and-clinicopathological-models - 2025-10-28

Developing and Launching a Research Participant Registry

A major challenge in clinical research today is the difficulty that studies have in meeting recruitment goals. Up to 48% of studies do not meet accrual goals within the specified timeframe, significantly delaying the progress of projects and the dissemination of findings. This pervasive problem is a recruitment crisis. We developed a representative, ethnically and racially diverse research partici

https://www.lupop.lu.se/article/developing-and-launching-research-participant-registry - 2025-10-28

National Spinal Cord Injury Registry of Iran (NSCIR-IR) – a critical appraisal of its strengths and weaknesses

The National Spinal Cord Injury Registry of Iran (NSCIR-IR) is a not-for-profit, hospital-based, and prospective observational registry that appraises the quality of care, long-term outcomes and the personal and psychological burden of traumatic spinal cord injury in Iran. Benchmarking validity in every registry includes rigorous attention to data quality. New publication in Chinese Journal of Tra

https://www.lupop.lu.se/article/national-spinal-cord-injury-registry-iran-nscir-ir-critical-appraisal-its-strengths-and-weaknesses - 2025-10-28

International Validation of the Danish Vascular Registry Karbase: A Vascunet Report

Vascunet has previously published an international comparison of registry data within vascular surgery. Data validity and completeness in participating registries is essential for a meaningful interpretation of differences between countries. The Vascunet collaboration has therefore developed a methodology for validation of international vascular registry data, previously used for validation of two

https://www.lupop.lu.se/article/international-validation-danish-vascular-registry-karbase-vascunet-report - 2025-10-28

Cause of death and significant disease found at autopsy

The use of clinical autopsy has been in decline for many years throughout healthcare systems of developed countries despite studies showing substantial discrepancies between autopsy results and pre-mortal clinical diagnoses. We conducted a study to evaluate over time the use and results of clinical autopsies in Sweden. We reviewed the autopsy reports and autopsy referrals of 2410 adult (age > 17)

https://www.lupop.lu.se/article/cause-death-and-significant-disease-found-autopsy - 2025-10-28

Swedish Inflammatory Bowel Disease Register (SWIBREG) – a nationwide quality register

Inflammatory bowel disease (IBD) is a chronic, inflammatory relapsing disease with increasing incidence. IBD research and long-term follow-up of patients have, however, been hampered by lack of detailed data on disease phenotype, patient-reported outcome measures, Physician Global Assessment, disease activity, and hospital-administered drugs. New publication in Scandinavian Journal of Gastroentero

https://www.lupop.lu.se/article/swedish-inflammatory-bowel-disease-register-swibreg-nationwide-quality-register - 2025-10-28

A colorectal cancer diet quality index is inversely associated with colorectal cancer in the Malmö diet and cancer study

The World Cancer Research Fund International has concluded strong evidence for that high intake of dairy products and foods containing dietary fiber and low intake of processed meat are associated with decreased risk of colorectal cancer (CRC). As food items are consumed together, it is important to study dietary patterns. New publication in European Journal of Cancer Prevention

https://www.lupop.lu.se/article/colorectal-cancer-diet-quality-index-inversely-associated-colorectal-cancer-malmo-diet-and-cancer - 2025-10-28

Role of healthcare databases and registries for surveillance of orphan drugs in the real-world setting: the Italian case study

Orphan drugs are medicines intended to treat, prevent, or diagnose a rare and serious condition. The collection of pre-marketing safety and efficacy data for orphan drugs is very challenging for several reasons related to the rarity of the diseases. This highlights the need for robust post-marketing evidence generation. Real-world data sources, such as claims databases, electronic healthcare recor

https://www.lupop.lu.se/article/role-healthcare-databases-and-registries-surveillance-orphan-drugs-real-world-setting-italian-case - 2025-10-28